Dear colleagues and friends,As we begin a new year, I would like to thank you for your continued engagement and trust in ECETOC. 2026 promises to be an exciting and dynamic year, and I am pleased...
Looking for an extra challenge? A next step to help develop your career? Consider applying for our Secondee Programme!ECETOC is looking for early-career scientists currently working at a member co...
This software was developed by a consortium of partners to facilitate the uptake of novel approaches to estimate aquatic threshold concentrations (e.g. the concentration at which 5% of the species are exposed above their EC50, HC5).
Why?Hazard and safety assessments for the pelagic compartment often rely on in vivo studies using a single fish species, raising ethical concerns and uncertainty in terms of extrapolation....
Why?REACH restriction: SPM use restricted; emissions reporting required by May 2027.
Gap: No analytical methods available to measure SPM emissions.
Solution: Draft SPERC-based approac...
Why?Validation of NAMs is often overlooked despite its importance for regulatory use.
Traditional validation methods are less suitable for NAMs, which focus on key events rather than apical...
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NGRA and NAMsThreshold of Toxicological Concern (TTC)
This report discusses the need for a systematic representation of knowledge about developmental toxicity (i.e. an ontology) that would enable computer-based prediction of which chemicals are likely to...
Chemical activity has recently been promoted as a useful concept for interpreting and classifying ecotoxicological data and for performing environmental risk assessment of chemicals. The most common...
ECETOC concept allows assessing the safety of nanomaterials undertaking animal testing only as a very last resortBrussels, December 2015The safety of nanomaterials can be ensured by testing...
Why?
The current paradigm for identifying data (study) requirements is based upon a surrogate of exposure, namely production volume, which may under or overestimate real exposure. As presented in ...
Why?
“Smart” or extended studies can be defined as in vivo studies that employ additional or different endpoints from conventional studies.They fall into 2 categories:those that follo...
Background
Recent opinions published by the RAC on low top dose selection in animal toxicity studies have indicated an apparent intent of increasing dosages systematically in view of the criteria u...
